Version 5.4
Homo sapiens Gene: GRID1
Summary
InnateDB Gene IDBG-80868.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GRID1
Gene Name glutamate receptor, ionotropic, delta 1
Synonyms GluD1;
Species Homo sapiens
Ensembl Gene ENSG00000182771
Encoded Proteins
IDBP-80872
glutamate receptor, ionotropic, delta 1
IDBP-603393
glutamate receptor, ionotropic, delta 1
IDBP-590553
glutamate receptor, ionotropic, delta 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:85599555-86366493
Strand Reverse strand
Band q23.2
Transcripts
ENST00000327946 ENSP00000330148
ENST00000464741 ENSP00000433064
ENST00000474115
ENST00000552278
ENST00000536331 ENSP00000444455
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004970 ionotropic glutamate receptor activity
GO:0005215 transporter activity
GO:0005234 extracellular-glutamate-gated ion channel activity
Biological Process
GO:0006810 transport
GO:0034220 ion transmembrane transport
GO:0035176 social behavior
GO:0035235 ionotropic glutamate receptor signaling pathway
GO:0035249 synaptic transmission, glutamatergic
Cellular Component
GO:0008328 ionotropic glutamate receptor complex
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030425 dendrite
GO:0045211 postsynaptic membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
ENSMUSG00000041078
View Gene Order
Ortholuge
SSD Ortholog
Ortholog supports species divergence
ENSBTAG00000019623
Not yet available
Ortholuge
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL G3V186
UniProt Splice Variant
Entrez Gene 2894
UniGene Hs.530653 Hs.568871
RefSeq NM_017551
HUGO HGNC:4575
OMIM 610659
CCDS CCDS31236
HPRD 17078
IMGT
EMBL AC022028 AC073162 AC079955 AL451059 AL596135 AL683834 AL732479 AL844892 CH471142
GenPept EAW80338
RNA Seq Atlas 2894

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca