Version 5.4
Homo sapiens Gene: CHRDL1
Summary
InnateDB Gene IDBG-82461.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHRDL1
Gene Name chordin-like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000101938
Encoded Proteins
IDBP-82463
chordin-like 1
IDBP-82467
chordin-like 1
IDBP-240857
chordin-like 1
IDBP-379289
chordin-like 1
IDBP-483871
chordin-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:110673856-110795819
Strand Reverse strand
Band q23
Transcripts
ENST00000372045 ENSP00000361115
ENST00000372042 ENSP00000361112
ENST00000394797 ENSP00000378276
ENST00000444321 ENSP00000399739
ENST00000482160 ENSP00000418443
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001503 ossification
GO:0001654 eye development
GO:0007399 nervous system development
GO:0030154 cell differentiation
GO:0030509 BMP signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0048749 compound eye development
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031283
View Gene Order
ENSBTAG00000004432
Not yet available
Pathways
NETPATH
REACTOME
REACT_12034
Signaling by BMP pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
bmppathway
BMP receptor signaling
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.496587
RefSeq NM_001143981 NM_001143982 NM_001143983 NM_145234 XM_005262221 XM_005262222 XM_005262223 XM_005262224
HUGO
OMIM
CCDS CCDS14553 CCDS48148 CCDS48149 CCDS48150
HPRD 02285
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca