Homo sapiens Gene: ALG13
Summary
InnateDB Gene IDBG-82767.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALG13
Gene Name asparagine-linked glycosylation 13 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000101901
Encoded Proteins
asparagine-linked glycosylation 13 homolog (S. cerevisiae)
asparagine-linked glycosylation 13 homolog (S. cerevisiae)
asparagine-linked glycosylation 13 homolog (S. cerevisiae)
asparagine-linked glycosylation 13 homolog (S. cerevisiae)
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
asparagine-linked glycosylation 13 homolog (S. cerevisiae)
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
asparagine-linked glycosylation 13 homolog (S. cerevisiae)
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG13, UDP-N-acetylglucosaminyltransferase subunit
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a subunit of a bipartite UDP-N-acetylglucosamine transferase. It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:111665811-111760649
Strand Forward strand
Band q23
Transcripts
ENST00000371979 ENSP00000361047
ENST00000251943 ENSP00000251943
ENST00000394780 ENSP00000378260
ENST00000436609 ENSP00000392990
ENST00000487141 ENSP00000478130
ENST00000473389 ENSP00000480711
ENST00000482374 ENSP00000479632
ENST00000486353 ENSP00000426892
ENST00000492038 ENSP00000479483
ENST00000489033 ENSP00000482257
ENST00000495283 ENSP00000427093
ENST00000471924 ENSP00000484523
ENST00000468657 ENSP00000480638
ENST00000482742 ENSP00000477513
ENST00000470704
ENST00000490774
ENST00000470971 ENSP00000479424
ENST00000460092
ENST00000486578
ENST00000461669
ENST00000474121 ENSP00000485400
ENST00000485371
ENST00000487243
ENST00000622997 ENSP00000485420
ENST00000624161 ENSP00000485181
ENST00000624881 ENSP00000485093
ENST00000622986 ENSP00000485067
ENST00000623144 ENSP00000485279
ENST00000623255 ENSP00000485333
ENST00000623148 ENSP00000485658
ENST00000623189 ENSP00000485392
ENST00000623622 ENSP00000485624
ENST00000623310 ENSP00000485071
ENST00000610588 ENSP00000479731
ENST00000621367 ENSP00000481509
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity
GO:0008234 cysteine-type peptidase activity
GO:0016758 transferase activity, transferring hexosyl groups
GO:0030246 carbohydrate binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006488 dolichol-linked oligosaccharide biosynthetic process
GO:0006508 proteolysis
GO:0018279 protein N-linked glycosylation via asparagine
GO:0030259 lipid glycosylation
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Post-translational protein modification pathway
Asparagine N-linked glycosylation pathway
Metabolism of proteins pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
KEGG
N-Glycan biosynthesis pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.443061
RefSeq NM_001039210 NM_001099922 NM_001168385 NM_001257230 NM_001257231 NM_001257234 NM_001257235 NM_001257237 NM_001257239 NM_001257240 NM_018466 XM_005262191 XM_006724695 XM_006724696 XM_006724697 XM_006724698 XM_006724699 XM_006724700 XM_006724702 XM_006724703
HUGO
OMIM
CCDS CCDS14559 CCDS55477 CCDS59173 CCDS76011 CCDS76012 CCDS76013
HPRD 06542
IMGT
EMBL
GenPept
RNA Seq Atlas