Version 5.4
Homo sapiens Gene: ALPPL2
Summary
InnateDB Gene IDBG-83222.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALPPL2
Gene Name alkaline phosphatase, placental-like 2
Synonyms ALPG; ALPPL; GCAP
Species Homo sapiens
Ensembl Gene ENSG00000163286
Encoded Proteins
IDBP-83224
alkaline phosphatase, placental-like 2
IDBP-808434
alkaline phosphatase, placental-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:232406843-232410714
Strand Forward strand
Band q37.1
Transcripts
ENST00000295453 ENSP00000295453
ENST00000611550 ENSP00000483564
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004035 alkaline phosphatase activity
GO:0016791 phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0008152 metabolic process
GO:0016311 dephosphorylation
Cellular Component
GO:0005886 plasma membrane
GO:0031225 anchored component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
hsa00790
Folate biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.333509
RefSeq NM_031313
HUGO
OMIM
CCDS CCDS2491
HPRD 01380
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca