Version 5.4
Homo sapiens Gene: SYCP2
Summary
InnateDB Gene IDBG-83505.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYCP2
Gene Name synaptonemal complex protein 2
Synonyms SCP2
Species Homo sapiens
Ensembl Gene ENSG00000196074
Encoded Proteins
IDBP-83507
synaptonemal complex protein 2
IDBP-83511
synaptonemal complex protein 2
IDBP-379854
synaptonemal complex protein 2
IDBP-379858
synaptonemal complex protein 2
IDBP-379863
synaptonemal complex protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. The protein encoded by this gene is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:59863563-59933655
Strand Reverse strand
Band q13.33
Transcripts
ENST00000371001 ENSP00000360040
ENST00000357552 ENSP00000350162
ENST00000412613 ENSP00000404358
ENST00000446834 ENSP00000402456
ENST00000425931 ENSP00000399300
ENST00000474749
ENST00000461538
ENST00000471331
ENST00000476314
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0007128 meiotic prophase I
GO:0007130 synaptonemal complex assembly
GO:0007140 male meiosis
GO:0007143 female meiotic division
GO:0009566 fertilization
GO:0009887 organ morphogenesis
GO:0043066 negative regulation of apoptotic process
GO:0048808 male genitalia morphogenesis
Cellular Component
GO:0000795 synaptonemal complex
GO:0000800 lateral element
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000060445
View Gene Order
ENSBTAG00000003608
Not yet available
Pathways
NETPATH
REACTOME
REACT_75792
Meiotic synapsis pathway
REACT_115566
Cell Cycle pathway
REACT_111183
Meiosis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.202676 Hs.605161
RefSeq NM_014258 XM_005260247 XM_006723681
HUGO
OMIM
CCDS CCDS13482
HPRD 06822
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca