Version 5.4
Homo sapiens Gene: ARL4C
Summary
InnateDB Gene IDBG-83975.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARL4C
Gene Name ADP-ribosylation factor-like 4C
Synonyms ARL7; LAK
Species Homo sapiens
Ensembl Gene ENSG00000188042
Encoded Proteins
IDBP-83977
ADP-ribosylation factor-like 4C
IDBP-83979
ADP-ribosylation factor-like 4C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary ADP-ribosylation factor-like 4C is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4C is closely similar to ARL4A and ARL4D and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in cholesterol transport. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:234493041-234497053
Strand Reverse strand
Band q37.1
Transcripts
ENST00000339728 ENSP00000339754
ENST00000390645 ENSP00000375057
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0043014 alpha-tubulin binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0032456 endocytic recycling
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0030175 filopodium
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000049866
View Gene Order
ENSBTAG00000045647
Not yet available
Cross-References
SwissProt P56559
TrEMBL A0A024R4C5
UniProt Splice Variant
Entrez Gene 10123
UniGene Hs.111554 Hs.592654 Hs.730678 Hs.740851
RefSeq NM_001282431 NM_005737
HUGO HGNC:698
OMIM 604787
CCDS CCDS2512 CCDS63169
HPRD
IMGT
EMBL AB016811 AC097713 AC105145 AF493892 AJ579850 AJ579851 AK314119 BC001051 BC089043 BT019378 BT019379 CH471063 Y17804
GenPept AAH89043 AAM12606 AAV38185 AAV38186 AAX93114 BAA75473 BAG36810 CAB44355 CAE30322 CAE30323 EAW71073 EAW71074
RNA Seq Atlas 10123

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca