Version 5.4
Homo sapiens Gene: PDCL
Summary
InnateDB Gene IDBG-84182.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDCL
Gene Name phosducin-like
Synonyms PhLP
Species Homo sapiens
Ensembl Gene ENSG00000136940
Encoded Proteins
IDBP-84184
phosducin-like
IDBP-241908
phosducin-like
IDBP-379698
phosducin-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:122798389-122828631
Strand Reverse strand
Band q33.2
Transcripts
ENST00000259467 ENSP00000259467
ENST00000394285 ENSP00000377826
ENST00000436632 ENSP00000397984
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005057 receptor signaling protein activity
GO:0032403 protein complex binding
Biological Process
GO:0006457 protein folding
GO:0007165 signal transduction
GO:0007601 visual perception
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway
GO:0035556 intracellular signal transduction
GO:0061084 negative regulation of protein refolding
GO:1902605 heterotrimeric G-protein complex assembly
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000009030
View Gene Order
ENSBTAG00000030675
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.271749
RefSeq NM_005388
HUGO
OMIM
CCDS CCDS6845
HPRD 05108
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca