Homo sapiens Gene: OR6B3
Summary
InnateDB Gene IDBG-84659.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OR6B3
Gene Name olfactory receptor, family 6, subfamily B, member 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000178586
Encoded Proteins
olfactory receptor, family 6, subfamily B, member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:240045077-240046072
Strand Reverse strand
Band q37.3
Transcripts
ENST00000319423 ENSP00000322435
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004984 olfactory receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0050911 detection of chemical stimulus involved in sensory perception of smell
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Olfactory Signaling Pathway pathway
KEGG
Olfactory transduction pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q8NGW1
TrEMBL I0EZ58
UniProt Splice Variant
Entrez Gene 150681
UniGene Hs.626616
RefSeq NM_173351
HUGO HGNC:15042
OMIM
CCDS CCDS42837
HPRD
IMGT
EMBL AB065662 BK004289 JQ411642
GenPept AFI24894 BAC05888 DAA04687
RNA Seq Atlas 150681