Version 5.4
Homo sapiens Gene: PPP1R7
Summary
InnateDB Gene IDBG-85045.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R7
Gene Name protein phosphatase 1, regulatory subunit 7
Synonyms SDS22
Species Homo sapiens
Ensembl Gene ENSG00000115685
Encoded Proteins
IDBP-85047
protein phosphatase 1, regulatory subunit 7
IDBP-85049
protein phosphatase 1, regulatory subunit 7
IDBP-295657
protein phosphatase 1, regulatory subunit 7
IDBP-292379
protein phosphatase 1, regulatory subunit 7
IDBP-295442
protein phosphatase 1, regulatory subunit 7
IDBP-292397
protein phosphatase 1, regulatory subunit 7
IDBP-294630
protein phosphatase 1, regulatory subunit 7
IDBP-389634
protein phosphatase 1, regulatory subunit 7
IDBP-389635
protein phosphatase 1, regulatory subunit 7
IDBP-389636
protein phosphatase 1, regulatory subunit 7
IDBP-389637
protein phosphatase 1, regulatory subunit 7
IDBP-389638
protein phosphatase 1, regulatory subunit 7
IDBP-389639
protein phosphatase 1, regulatory subunit 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein subunit that regulates the activity of the serine/threonine phosphatase, protein phosphatase-1. The encoded protein is required for completion of the mitotic cycle and for targeting protein phosphatase-1 to mitotic kinetochores. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:241149576-241183652
Strand Forward strand
Band q37.3
Transcripts
ENST00000272983 ENSP00000272983
ENST00000234038 ENSP00000234038
ENST00000402734 ENSP00000385012
ENST00000407025 ENSP00000385657
ENST00000404405 ENSP00000385498
ENST00000406106 ENSP00000385022
ENST00000401987 ENSP00000385466
ENST00000438799 ENSP00000396376
ENST00000423280 ENSP00000412092
ENST00000439916 ENSP00000409719
ENST00000427172 ENSP00000397985
ENST00000450367 ENSP00000392373
ENST00000415769 ENSP00000413360
ENST00000473017
ENST00000498170
ENST00000493374
ENST00000467159
ENST00000485630
ENST00000491715
ENST00000479821
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
Experimentally validated
Total 23 [view]
Protein-Protein 20 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008599 protein phosphatase type 1 regulator activity
GO:0030234 enzyme regulator activity
Biological Process
GO:0008150 biological_process
GO:0035307 positive regulation of protein dephosphorylation
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026275
View Gene Order
ENSBTAG00000000789
Not yet available
Cross-References
SwissProt
TrEMBL H7C118
UniProt Splice Variant
Entrez Gene 5510
UniGene Hs.36587
RefSeq NM_001282409 NM_001282410 NM_001282411 NM_001282412 NM_001282413 NM_001282414 NM_002712
HUGO HGNC:9295
OMIM 602877
CCDS CCDS2546 CCDS63190 CCDS63192 CCDS63193 CCDS63194
HPRD 04192
IMGT
EMBL AC005237
GenPept
RNA Seq Atlas 5510

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca