InnateDB Gene
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IDBG-85619.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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APLN
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Gene Name
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apelin
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Synonyms
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APEL; XNPEP2
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Species
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Homo sapiens
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Ensembl Gene
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ENSG00000171388
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Encoded Proteins
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|
Protein Structure
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Useful resources
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Stemformatics
EHFPI
ImmGen
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Summary |
This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.[provided by RefSeq, Feb 2010]
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Type |
Protein coding
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Genomic Location
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Chromosome X:129645809-129654937
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Strand
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Reverse strand
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Band
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q26.1
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Transcripts
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
2
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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|
|
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No orthologs found for this gene |
SwissProt
|
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TrEMBL
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B2R550
D3DTF8
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UniProt Splice Variant
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Entrez Gene
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8862
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UniGene
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Hs.303084
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RefSeq
|
NM_017413
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HUGO
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HGNC:16665
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OMIM
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300297
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CCDS
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HPRD |
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IMGT
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EMBL
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AK312061
AL022162
CH471107
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GenPept
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BAG34997
EAX11828
EAX11829
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RNA Seq Atlas
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8862
|
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