Homo sapiens Gene: APLN
Summary
InnateDB Gene IDBG-85619.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APLN
Gene Name apelin
Synonyms APEL; XNPEP2;
Species Homo sapiens
Ensembl Gene ENSG00000171388
Encoded Proteins
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.[provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:129645809-129654937
Strand Reverse strand
Band q26.1
Transcripts
ENST00000429967 ENSP00000391800
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.303084
RefSeq NM_017413
HUGO
OMIM
CCDS
HPRD 02246
IMGT
EMBL
GenPept
RNA Seq Atlas