Homo sapiens Gene: KCNK17
Summary
InnateDB Gene IDBG-86191.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNK17
Gene Name potassium channel, subfamily K, member 17
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000124780
Encoded Proteins
potassium channel, subfamily K, member 17
potassium channel, subfamily K, member 17
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is activated at alkaline pH. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:39299001-39314553
Strand Reverse strand
Band p21.2
Transcripts
ENST00000373231 ENSP00000362328
ENST00000453413 ENSP00000401271
ENST00000503878
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005244 voltage-gated ion channel activity
GO:0005267 potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0007268 synaptic transmission
GO:0034765 regulation of ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
TWIK-related alkaline pH activated K+ channel (TALK) pathway
Tandem pore domain potassium channels pathway
Neuronal System pathway
Potassium Channels pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q96T54
TrEMBL
UniProt Splice Variant
Entrez Gene 89822
UniGene Hs.162282
RefSeq NM_001135111 NM_031460 XM_006715239
HUGO HGNC:14465
OMIM 607370
CCDS CCDS47419 CCDS4842
HPRD
IMGT
EMBL AF339912 AF358910 AL136087 AY358853 BC025726
GenPept AAH25726 AAK28551 AAK49533 AAQ89212 CAI19536
RNA Seq Atlas 89822