Version 5.4
Homo sapiens Gene: TFDP3
Summary
InnateDB Gene IDBG-86712.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TFDP3
Gene Name transcription factor Dp family, member 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000183434
Encoded Proteins
IDBP-294900
transcription factor Dp family, member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the DP family of transcription factors. These factors heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. This protein functions as a negative regulator and inhibits the DNA binding and transcriptional activities of E2F factors.[provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:133216669-133218348
Strand Reverse strand
Band q26.2
Transcripts
ENST00000310125 ENSP00000385461
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000082 G1/S transition of mitotic cell cycle
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006974 cellular response to DNA damage stimulus
GO:0007049 cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q5H9I0
TrEMBL
UniProt Splice Variant
Entrez Gene 51270
UniGene Hs.142908
RefSeq NM_016521
HUGO HGNC:24603
OMIM 300772
CCDS CCDS14636
HPRD 06623
IMGT
EMBL AF219119 CH471107 Z77249
GenPept AAF37562 CAI42694 EAX11773
RNA Seq Atlas 51270

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca