Homo sapiens Gene: CNNM2
Summary
InnateDB Gene IDBG-88291.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CNNM2
Gene Name cyclin M2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000148842
Encoded Proteins
cyclin M2
cyclin M2
cyclin M2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in this gene are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:102918293-103090221
Strand Forward strand
Band q24.32
Transcripts
ENST00000369878 ENSP00000358894
ENST00000369875 ENSP00000358891
ENST00000433628 ENSP00000392875
ENST00000475511
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0030554 adenyl nucleotide binding
Biological Process
GO:0010960 magnesium ion homeostasis
GO:0015693 magnesium ion transport
Cellular Component
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.743405
RefSeq NM_017649 NM_199076 NM_199077 XM_005269933 XM_006717908
HUGO
OMIM
CCDS CCDS44474 CCDS44475 CCDS7543
HPRD 07418
IMGT
EMBL
GenPept
RNA Seq Atlas