Homo sapiens Gene: PDCD11
Summary
InnateDB Gene IDBG-88493.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDCD11
Gene Name programmed cell death 11
Synonyms ALG-4; ALG4; NFBP; RRP5;
Species Homo sapiens
Ensembl Gene ENSG00000148843
Encoded Proteins
programmed cell death 11
programmed cell death 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 [PubMed 14624448]; Sweet et al., 2008 [PubMed 17654514]).[supplied by OMIM, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:103396648-103446292
Strand Forward strand
Band q24.33
Transcripts
ENST00000369797 ENSP00000358812
ENST00000493610 ENSP00000474606
ENST00000471061
ENST00000490787
ENST00000466959
ENST00000478543
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0006397 mRNA processing
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q14690
TrEMBL S4R3Q4
UniProt Splice Variant
Entrez Gene 22984
UniGene Hs.239499 Hs.701461
RefSeq NM_014976 XM_005269647
HUGO HGNC:13408
OMIM 612333
CCDS CCDS31276
HPRD
IMGT
EMBL AL139339 AL591408 AL603983 AY007124 BC049838 BC064486 BC080560 BC111040 CH471066 D80007
GenPept AAG01992 AAH49838 AAH64486 AAH80560 AAI11041 BAA11502 CAH71487 CAI15102 CAI16749 EAW49641
RNA Seq Atlas 22984