Version 5.4
Homo sapiens Gene: SRPK3
Summary
InnateDB Gene IDBG-89947.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SRPK3
Gene Name SRSF protein kinase 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000184343
Encoded Proteins
IDBP-89949
SRSF protein kinase 3
IDBP-89951
SRSF protein kinase 3
IDBP-89953
SRSF protein kinase 3
IDBP-89955
SRSF protein kinase 3
IDBP-242906
SRSF protein kinase 3
IDBP-383023
SRSF protein kinase 3
IDBP-383025
SRSF protein kinase 3
IDBP-484844
SRSF protein kinase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:153776412-153785732
Strand Forward strand
Band q28
Transcripts
ENST00000370108 ENSP00000359126
ENST00000370104 ENSP00000359122
ENST00000370101 ENSP00000359119
ENST00000370100 ENSP00000359118
ENST00000393786 ENSP00000377376
ENST00000430541 ENSP00000402300
ENST00000458681 ENSP00000406166
ENST00000489426 ENSP00000420058
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 64 experimentally validated interaction(s) in this database.
Experimentally validated
Total 64 [view]
Protein-Protein 64 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0007519 skeletal muscle tissue development
GO:0030154 cell differentiation
GO:0060537 muscle tissue development
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000002007
View Gene Order
ENSBTAG00000001058
Not yet available
Cross-References
SwissProt Q9UPE1
TrEMBL
UniProt Splice Variant
Entrez Gene 26576
UniGene Hs.104865
RefSeq NM_014370 NM_001170760 NM_001170761
HUGO HGNC:11402
OMIM
CCDS CCDS35441 CCDS55537 CCDS55538
HPRD 06731
IMGT
EMBL AF027406 AK301749 BC092416 BC117124 DQ099381 U52111 U82808
GenPept AAD00539 AAD01848 AAH92416 AAI17125 AAZ13757 BAG63211
RNA Seq Atlas 26576

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca