Version 5.4
Homo sapiens Gene: MEP1A
Summary
InnateDB Gene IDBG-90012.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MEP1A
Gene Name meprin A, alpha (PABA peptide hydrolase)
Synonyms PPHA
Species Homo sapiens
Ensembl Gene ENSG00000112818
Encoded Proteins
IDBP-90014
meprin A, alpha (PABA peptide hydrolase)
IDBP-807103
meprin A, alpha (PABA peptide hydrolase)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:46793390-46839782
Strand Forward strand
Band p12.3
Transcripts
ENST00000230588 ENSP00000230588
ENST00000611727 ENSP00000480465
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0007586 digestion
Cellular Component
GO:0005615 extracellular space
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0017090 meprin A complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000023914
View Gene Order
ENSBTAG00000004345
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04974
Protein digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL B7ZL91
UniProt Splice Variant
Entrez Gene 4224
UniGene
RefSeq NM_005588
HUGO HGNC:7015
OMIM 600388
CCDS CCDS4918
HPRD
IMGT
EMBL BC143651
GenPept AAI43652
RNA Seq Atlas 4224

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca