Version 5.4
Homo sapiens Gene: MRFAP1
Summary
InnateDB Gene IDBG-9024.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRFAP1
Gene Name Morf4 family associated protein 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000179010
Encoded Proteins
IDBP-9026
Morf4 family associated protein 1
IDBP-9028
Morf4 family associated protein 1
IDBP-477849
Morf4 family associated protein 1
IDBP-813648
Morf4 family associated protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an intracellular protein that interacts with members of the MORF4/MRG (mortality factor on chromosome 4/MORF4 related gene) family and the tumor suppressor Rb (retinoblastoma protein.) The protein may play a role in senescence, cell growth and immortalization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:6640091-6642745
Strand Forward strand
Band p16.1
Transcripts
ENST00000320912 ENSP00000318352
ENST00000382581 ENSP00000372024
ENST00000507420 ENSP00000422065
ENST00000512914
ENST00000617365 ENSP00000478229
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 23 [view]
Protein-Protein 23 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000055302
View Gene Order
ENSBTAG00000046936
Not yet available
Cross-References
SwissProt Q9Y605
TrEMBL
UniProt Splice Variant
Entrez Gene 93621
UniGene Hs.727355
RefSeq NM_001272053 NM_001272054 NM_033296
HUGO HGNC:24549
OMIM
CCDS CCDS3389
HPRD
IMGT
EMBL AF116272 AK123360 BC022797 CH471131 CR457144
GenPept AAD38498 AAH22797 BAG53894 CAG33425 EAW82386 EAW82387
RNA Seq Atlas 93621

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca