Homo sapiens Gene: NAA10
Summary
InnateDB Gene IDBG-90615.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NAA10
Gene Name N(alpha)-acetyltransferase 10, NatA catalytic subunit
Synonyms ARD1; ARD1A; ARD1P; DXS707; MCOPS1; NATD; TE2;
Species Homo sapiens
Ensembl Gene ENSG00000102030
Encoded Proteins
N(alpha)-acetyltransferase 10, NatA catalytic subunit
N(alpha)-acetyltransferase 10, NatA catalytic subunit
N(alpha)-acetyltransferase 10, NatA catalytic subunit
N(alpha)-acetyltransferase 10, NatA catalytic subunit
N(alpha)-acetyltransferase 10, NatA catalytic subunit
N(alpha)-acetyltransferase 10, NatA catalytic subunit
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer of an acetyl group from acetyl-coenzyme A to the alpha-amino group on a nascent polypeptide and is essential for normal cell function. This gene encodes an N-terminal acetyltransferase that functions as the catalytic subunit of the major amino-terminal acetyltransferase A complex. Mutations in this gene are the cause of Ogden syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome X:153929242-153935223
Strand Reverse strand
Band q28
Transcripts
ENST00000370015 ENSP00000359032
ENST00000370011 ENSP00000359028
ENST00000370009 ENSP00000359026
ENST00000393712 ENSP00000377315
ENST00000393710
ENST00000432089 ENSP00000413668
ENST00000464845 ENSP00000417763
ENST00000482485
ENST00000466877
ENST00000484950
ENST00000460996
ENST00000467451
ENST00000477750
ENST00000477882
ENST00000478177
ENST00000488481
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 35 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 35 [view]
Protein-Protein 32 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004596 peptide alpha-N-acetyltransferase activity
GO:0005515 protein binding
GO:0008080 N-acetyltransferase activity
GO:0016407 acetyltransferase activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
GO:0043022 ribosome binding
Biological Process
GO:0006323 DNA packaging
GO:0006474 N-terminal protein amino acid acetylation
GO:0006475 internal protein amino acid acetylation
GO:0008152 metabolic process
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0031415 NatA complex
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001256119 NM_001256120 NM_003491
HUGO
OMIM
CCDS CCDS14737 CCDS59179
HPRD 02056
IMGT
EMBL
GenPept
RNA Seq Atlas