Version 5.4
Homo sapiens Gene: ATE1
Summary
InnateDB Gene IDBG-91597.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATE1
Gene Name arginyltransferase 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000107669
Encoded Proteins
IDBP-91599
arginyltransferase 1
IDBP-91601
arginyltransferase 1
IDBP-91603
arginyltransferase 1
IDBP-386301
arginyltransferase 1
IDBP-386303
arginyltransferase 1
IDBP-591308
arginyltransferase 1
IDBP-593350
arginyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:121740421-121928801
Strand Reverse strand
Band q26.13
Transcripts
ENST00000369043 ENSP00000358039
ENST00000369040 ENSP00000358036
ENST00000224652 ENSP00000224652
ENST00000423243 ENSP00000397787
ENST00000455628 ENSP00000405099
ENST00000485281
ENST00000481784
ENST00000540606 ENSP00000440881
ENST00000543447 ENSP00000444852
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004057 arginyltransferase activity
GO:0005515 protein binding
Biological Process
GO:0016598 protein arginylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030850
View Gene Order
ENSBTAG00000003178
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.614278 Hs.632080 Hs.635094
RefSeq NM_001001976 NM_001288734 NM_001288735 NM_001288736 NM_007041 XM_005269460 XM_005269461
HUGO
OMIM
CCDS CCDS31299 CCDS31300 CCDS73211 CCDS73212 CCDS73213
HPRD 06979
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca