Homo sapiens Gene: RAB23
Summary
InnateDB Gene IDBG-91614.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAB23
Gene Name RAB23, member RAS oncogene family
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000112210
Encoded Proteins
RAB23, member RAS oncogene family
RAB23, member RAS oncogene family
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It may be involved in small GTPase mediated signal transduction and intracellular protein transportation. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:57186992-57222314
Strand Reverse strand
Band p11.2
Transcripts
ENST00000317483 ENSP00000320413
ENST00000468148 ENSP00000417610
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0000045 autophagic vacuole assembly
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0006968 cellular defense response
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0007399 nervous system development
GO:0008589 regulation of smoothened signaling pathway
GO:0015031 protein transport
GO:0021513 spinal cord dorsal/ventral patterning
GO:0042733 embryonic digit morphogenesis
GO:0042992 negative regulation of transcription factor import into nucleus
GO:0045861 negative regulation of proteolysis
GO:0097094 craniofacial suture morphogenesis
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005776 autophagic vacuole
GO:0005886 plasma membrane
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0030670 phagocytic vesicle membrane
GO:0045335 phagocytic vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
Hedgehog pathway
REACTOME
KEGG
Hedgehog signaling pathway pathway
INOH
PID BIOCARTA
PID NCI
Hedgehog signaling events mediated by Gli proteins
Cross-References
SwissProt Q9ULC3
TrEMBL A0A024RD41
UniProt Splice Variant
Entrez Gene 51715
UniGene Hs.555016 Hs.594199
RefSeq NM_001278666 NM_001278667 NM_016277 XM_005249179 NM_001278668 NM_183227
HUGO HGNC:14263
OMIM 606144
CCDS CCDS4962
HPRD 05850
IMGT
EMBL AB025427 AB034244 AF161486 AF498951 AK313796 AL031321 AY585189 BC015021 CH471081 CR749371
GenPept AAF29101 AAH15021 AAM21099 AAT79492 BAA87324 BAB40309 BAG36532 CAH18224 CAI21564 EAX04476 EAX04478 EAX04479
RNA Seq Atlas 51715