Version 5.4
Homo sapiens Gene: ZBTB1
Summary
InnateDB Gene IDBG-9178.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZBTB1
Gene Name zinc finger and BTB domain containing 1
Synonyms ZNF909
Species Homo sapiens
Ensembl Gene ENSG00000126804
Encoded Proteins
IDBP-9180
zinc finger and BTB domain containing 1
IDBP-604197
zinc finger and BTB domain containing 1
IDBP-604198
zinc finger and BTB domain containing 1
IDBP-604199
zinc finger and BTB domain containing 1
IDBP-604200
zinc finger and BTB domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:64503712-64533690
Strand Forward strand
Band q23.3
Transcripts
ENST00000358738 ENSP00000351587
ENST00000556818
ENST00000553583 ENSP00000451584
ENST00000556965 ENSP00000450689
ENST00000554015 ENSP00000451000
ENST00000555321 ENSP00000451332
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 89 experimentally validated interaction(s) in this database.
Experimentally validated
Total 89 [view]
Protein-Protein 89 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0002711 positive regulation of T cell mediated immunity
GO:0030183 B cell differentiation
GO:0032825 positive regulation of natural killer cell differentiation
GO:0033077 T cell differentiation in thymus
GO:0042789 mRNA transcription from RNA polymerase II promoter
GO:0045087 innate immune response
GO:0045582 positive regulation of T cell differentiation
GO:0048538 thymus development
GO:0051260 protein homooligomerization
GO:2000176 positive regulation of pro-T cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0016604 nuclear body
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033454
View Gene Order
ENSBTAG00000040551
Not yet available
Cross-References
SwissProt
TrEMBL G3V3N0
UniProt Splice Variant
Entrez Gene 22890
UniGene Hs.605143 Hs.723486
RefSeq NM_001123329 NM_014950 XM_005267410 XM_005267411
HUGO HGNC:20259
OMIM
CCDS CCDS32097 CCDS45126
HPRD 15688
IMGT
EMBL AL049869
GenPept
RNA Seq Atlas 22890

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca