Homo sapiens Gene: COL19A1
Summary
InnateDB Gene IDBG-91912.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COL19A1
Gene Name collagen, type XIX, alpha 1
Synonyms COL9A1L; D6S228E;
Species Homo sapiens
Ensembl Gene ENSG00000082293
Encoded Proteins
collagen, type XIX, alpha 1
collagen, type XIX, alpha 1
collagen, type XIX, alpha 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Although the function of this collagen is not known, other members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. The transcript produced from this gene has an unusually large 3' UTR which has not been completely sequenced. [provided by RefSeq, Jul 2008]
This gene encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Although the function of this collagen is not known, other members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. The transcript produced from this gene has an unusually large 3\' UTR which has not been completely sequenced. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:69866571-70209976
Strand Forward strand
Band q13
Transcripts
ENST00000455415 ENSP00000416556
ENST00000478620 ENSP00000479481
ENST00000476656
ENST00000483745
ENST00000620364 ENSP00000480474
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005201 extracellular matrix structural constituent
GO:0030674 protein binding, bridging
Biological Process
GO:0001501 skeletal system development
GO:0007155 cell adhesion
GO:0007519 skeletal muscle tissue development
GO:0016337 single organismal cell-cell adhesion
GO:0022617 extracellular matrix disassembly
GO:0030154 cell differentiation
GO:0030198 extracellular matrix organization
GO:0030574 collagen catabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005581 collagen trimer
GO:0005788 endoplasmic reticulum lumen
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Collagen biosynthesis and modifying enzymes pathway
Extracellular matrix organization pathway
Degradation of the extracellular matrix pathway
Collagen degradation pathway
Collagen formation pathway
KEGG
INOH
Integrin signaling pathway pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q14993
TrEMBL Q5JVU1
UniProt Splice Variant
Entrez Gene 1310
UniGene Hs.444842 Hs.601816 Hs.679739
RefSeq NM_001858
HUGO HGNC:2196
OMIM 120165
CCDS CCDS4970
HPRD
IMGT
EMBL AB004629 AH000850 AL118519 AL133388 AL136445 AL160262 AL359539 BC113362 BC113364 D38163 L12347 M63597 U09279
GenPept AAA21146 AAA21147 AAA36358 AAA58468 AAI13363 AAI13365 BAA07368 BAA23309 CAB99331 CAC12699 CAI16492 CAI42319 CAI42322 CAI42496 CAI42497 CAI42716
RNA Seq Atlas 1310