InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: COL19A1

Summary

InnateDB Gene

IDBG-91912.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

COL19A1

Gene Name

collagen, type XIX, alpha 1

Synonyms

COL9A1L; D6S228E

Species

Homo sapiens

Ensembl Gene

ENSG00000082293

Encoded Proteins

IDBP-382658

collagen, type XIX, alpha 1

IDBP-808872

collagen, type XIX, alpha 1

IDBP-808871

collagen, type XIX, alpha 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Although the function of this collagen is not known, other members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. The transcript produced from this gene has an unusually large 3' UTR which has not been completely sequenced. [provided by RefSeq, Jul 2008]
This gene encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Although the function of this collagen is not known, other members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. The transcript produced from this gene has an unusually large 3\' UTR which has not been completely sequenced. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:69866571-70209976

Strand

Forward strand

Band

q13

Transcripts

ENST00000455415	ENSP00000416556
ENST00000478620	ENSP00000479481
ENST00000476656
ENST00000483745
ENST00000620364	ENSP00000480474

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005201	extracellular matrix structural constituent
GO:0030674	protein binding, bridging

Biological Process

GO:0001501	skeletal system development
GO:0007155	cell adhesion
GO:0007519	skeletal muscle tissue development
GO:0016337	single organismal cell-cell adhesion
GO:0022617	extracellular matrix disassembly
GO:0030154	cell differentiation
GO:0030198	extracellular matrix organization
GO:0030574	collagen catabolic process

Cellular Component

GO:0005576	extracellular region
GO:0005578	proteinaceous extracellular matrix
GO:0005581	collagen trimer
GO:0005788	endoplasmic reticulum lumen

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000026141

View Gene Order

ENSBTAG00000020991

Not yet available

Pathways

NETPATH

REACTOME

REACT_121139

Collagen biosynthesis and modifying enzymes pathway

REACT_150401

Collagen degradation pathway

REACT_118779

Extracellular matrix organization pathway

REACT_118572

Degradation of the extracellular matrix pathway

REACT_120729

Collagen formation pathway

KEGG

INOH

INOH website

Integrin signaling pathway pathway

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Hs.444842 Hs.601816 Hs.679739

RefSeq

NM_001858

HUGO

OMIM

CCDS

CCDS4970

HPRD

00364

IMGT

EMBL

GenPept

RNA Seq Atlas