Homo sapiens Gene: MRPS2
Summary
InnateDB Gene IDBG-91936.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRPS2
Gene Name mitochondrial ribosomal protein S2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000122140
Encoded Proteins
mitochondrial ribosomal protein S2
mitochondrial ribosomal protein S2
mitochondrial ribosomal protein S2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:135499984-135504673
Strand Forward strand
Band q34.3
Transcripts
ENST00000371785 ENSP00000360850
ENST00000241600 ENSP00000241600
ENST00000453385 ENSP00000400082
ENST00000488610
ENST00000485333
ENST00000462948
ENST00000472852
ENST00000472946
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005622 intracellular
GO:0005739 mitochondrion
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Ribosome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL Q5T8A0 Q96Q47
UniProt Splice Variant
Entrez Gene 51116
UniGene
RefSeq NM_016034 XM_006717136
HUGO HGNC:14495
OMIM 611971
CCDS CCDS6990
HPRD 14783
IMGT
EMBL AB051627 AL161452
GenPept BAB54954
RNA Seq Atlas 51116