Homo sapiens Gene: PNPLA7
Summary
InnateDB Gene IDBG-93426.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PNPLA7
Gene Name patatin-like phospholipase domain containing 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000130653
Encoded Proteins
patatin-like phospholipase domain containing 7
patatin-like phospholipase domain containing 7
patatin-like phospholipase domain containing 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Human patatin-like phospholipases, such as PNPLA7, have been implicated in regulation of adipocyte differentiation and have been induced by metabolic stimuli (Wilson et al., 2006 [PubMed 16799181]).[supplied by OMIM, Jun 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:137459953-137550534
Strand Reverse strand
Band q34.3
Transcripts
ENST00000277531 ENSP00000277531
ENST00000406427 ENSP00000384610
ENST00000434090
ENST00000492278
ENST00000469998
ENST00000487228
ENST00000491019 ENSP00000436165
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004622 lysophospholipase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0008152 metabolic process
Cellular Component
GO:0005765 lysosomal membrane
GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
GO:0031966 mitochondrial membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Glycerophospholipid metabolism pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL F2Z2D4
UniProt Splice Variant
Entrez Gene 375775
UniGene
RefSeq NM_152286 NM_001098537 XM_006717104 XM_006717102
HUGO HGNC:24768
OMIM 612122
CCDS CCDS7045 CCDS48070
HPRD 12933
IMGT
EMBL AL365502
GenPept
RNA Seq Atlas 375775