Version 5.4
Homo sapiens Gene: PNPLA7
Summary
InnateDB Gene IDBG-93426.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PNPLA7
Gene Name patatin-like phospholipase domain containing 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000130653
Encoded Proteins
IDBP-93430
patatin-like phospholipase domain containing 7
IDBP-293755
patatin-like phospholipase domain containing 7
IDBP-598026
patatin-like phospholipase domain containing 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Human patatin-like phospholipases, such as PNPLA7, have been implicated in regulation of adipocyte differentiation and have been induced by metabolic stimuli (Wilson et al., 2006 [PubMed 16799181]).[supplied by OMIM, Jun 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:137459953-137550534
Strand Reverse strand
Band q34.3
Transcripts
ENST00000277531 ENSP00000277531
ENST00000406427 ENSP00000384610
ENST00000434090
ENST00000492278
ENST00000469998
ENST00000487228
ENST00000491019 ENSP00000436165
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004622 lysophospholipase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0008152 metabolic process
Cellular Component
GO:0005765 lysosomal membrane
GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
GO:0031966 mitochondrial membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036833
View Gene Order
ENSBTAG00000012126
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00564
Glycerophospholipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001098537 NM_152286 XM_006717102 XM_006717104
HUGO
OMIM
CCDS CCDS48070 CCDS7045
HPRD 12933
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca