Version 5.4
Homo sapiens Gene: KNDC1
Summary
InnateDB Gene IDBG-93571.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KNDC1
Gene Name kinase non-catalytic C-lobe domain (KIND) containing 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000171798
Encoded Proteins
IDBP-93575
kinase non-catalytic C-lobe domain (KIND) containing 1
IDBP-93577
kinase non-catalytic C-lobe domain (KIND) containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 10:133160447-133226412
Strand Forward strand
Band q26.3
Transcripts
ENST00000304613 ENSP00000304437
ENST00000368571 ENSP00000357560
ENST00000478074
ENST00000485110
ENST00000530127
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004674 protein serine/threonine kinase activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0001934 positive regulation of protein phosphorylation
GO:0006468 protein phosphorylation
GO:0007264 small GTPase mediated signal transduction
GO:0008150 biological_process
GO:0008152 metabolic process
GO:0021707 cerebellar granule cell differentiation
GO:0032318 regulation of Ras GTPase activity
GO:0043547 positive regulation of GTPase activity
GO:0048814 regulation of dendrite morphogenesis
GO:0050773 regulation of dendrite development
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005575 cellular_component
GO:0005622 intracellular
GO:0030425 dendrite
GO:0032045 guanyl-nucleotide exchange factor complex
GO:0043025 neuronal cell body
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000066129
View Gene Order
ENSBTAG00000011092
Not yet available
Cross-References
SwissProt Q76NI1
TrEMBL B4DFN0 E7ETM1
UniProt Splice Variant
Entrez Gene 85442
UniGene Hs.530685
RefSeq NM_152643
HUGO HGNC:29374
OMIM
CCDS CCDS7674
HPRD
IMGT
EMBL AB000781 AB051555 AK057756 AK074179 AK131205 AK294170 AL445199
GenPept BAB21859 BAB71561 BAB85005 BAD12625 BAD18397 BAG57491 CAI17339 CAM24665
RNA Seq Atlas 85442

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca