Version 5.4
Homo sapiens Gene: HTR1D
Summary
InnateDB Gene IDBG-93832.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HTR1D
Gene Name 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
Synonyms 5-HT1D; HT1DA; HTR1DA; HTRL; RDC4
Species Homo sapiens
Ensembl Gene ENSG00000179546
Encoded Proteins
IDBP-93836
5-hydroxytryptamine (serotonin) receptor 1D
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:23191895-23194729
Strand Reverse strand
Band p36.12
Transcripts
ENST00000374619 ENSP00000363748
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004993 serotonin receptor activity
GO:0051378 serotonin binding
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007268 synaptic transmission
GO:0009636 response to toxic substance
GO:0014827 intestine smooth muscle contraction
GO:0040012 regulation of locomotion
GO:0042310 vasoconstriction
GO:0050795 regulation of behavior
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000070687
View Gene Order
ENSBTAG00000040329
Not yet available
Pathways
NETPATH
REACTOME
REACT_19231
G alpha (i) signalling events pathway
REACT_17064
Serotonin receptors pathway
REACT_16983
Amine ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt P28221
TrEMBL
UniProt Splice Variant
Entrez Gene 3352
UniGene Hs.121482
RefSeq NM_000864
HUGO HGNC:5289
OMIM 182133
CCDS CCDS231
HPRD
IMGT
EMBL AF498979 AL049576 BC007720 BT007027 M81589 M89955
GenPept AAA35491 AAA60315 AAH07720 AAM21126 AAP35673 CAB81617
RNA Seq Atlas 3352

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca