Version 5.4
Homo sapiens Gene: MECR
Summary
InnateDB Gene IDBG-95333.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MECR
Gene Name mitochondrial trans-2-enoyl-CoA reductase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000116353
Encoded Proteins
IDBP-95335
mitochondrial trans-2-enoyl-CoA reductase
IDBP-95339
mitochondrial trans-2-enoyl-CoA reductase
IDBP-602286
mitochondrial trans-2-enoyl-CoA reductase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:29192873-29230942
Strand Reverse strand
Band p35.3
Transcripts
ENST00000263702 ENSP00000263702
ENST00000373791 ENSP00000362896
ENST00000453185
ENST00000475773
ENST00000483435
ENST00000473030
ENST00000478505
ENST00000463412 ENSP00000436831
ENST00000490529
ENST00000464511
ENST00000463052
ENST00000489248
ENST00000475861
ENST00000474946
ENST00000464915
ENST00000482610
ENST00000484012
ENST00000493928
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity
Biological Process
GO:0006631 fatty acid metabolic process
GO:0006633 fatty acid biosynthetic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028910
View Gene Order
ENSBTAG00000017253
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00062
Fatty acid elongation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.183646
RefSeq NM_001024732 NM_016011 XM_005245886 XM_005245887 XM_005245888 XM_005245889 XM_006710674
HUGO
OMIM
CCDS CCDS30659 CCDS30660
HPRD 12192
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca