Homo sapiens Gene: KLHL7
Summary
InnateDB Gene IDBG-9558.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KLHL7
Gene Name kelch-like 7 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000122550
Encoded Proteins
kelch-like 7 (Drosophila)
kelch-like 7 (Drosophila)
kelch-like 7 (Drosophila)
kelch-like 7 (Drosophila)
kelch-like 7 (Drosophila)
kelch-like 7 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a BTB-Kelch-related protein. The encoded protein may be involved in protein degradation. Mutations in this gene have been associated with retinitis pigmentosa 42. [provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:23105758-23177914
Strand Forward strand
Band p15.3
Transcripts
ENST00000339077 ENSP00000343273
ENST00000322275 ENSP00000323270
ENST00000410047 ENSP00000386999
ENST00000409689 ENSP00000386263
ENST00000414163 ENSP00000404181
ENST00000479288
ENST00000521082 ENSP00000430351
ENST00000459661
ENST00000491352
ENST00000479700
ENST00000477076
ENST00000469576
ENST00000469845
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0031463 Cul3-RING ubiquitin ligase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q8IXQ5
TrEMBL E5RFN1
UniProt Splice Variant
Entrez Gene 55975
UniGene Hs.654817 Hs.708589
RefSeq NM_001172428 NM_001031710 NM_018846
HUGO HGNC:15646
OMIM 611119
CCDS CCDS55095 CCDS34609 CCDS5378
HPRD 13927
IMGT
EMBL AC005082 AC006039 AC073992 AF111113 AK056390 AK299006 AL136597 BC009555 BC039585 CH236948 CH471073 EF560731
GenPept AAF27196 AAH09555 AAH39585 AAO21916 ABQ59041 BAB71175 BAH12925 CAB66532 EAL24261 EAW93770 EAW93773 EAW93774
RNA Seq Atlas 55975