Homo sapiens Gene: RNF19B
Summary
InnateDB Gene IDBG-95845.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNF19B
Gene Name ring finger protein 19B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000116514
Encoded Proteins
ring finger protein 19B
ring finger protein 19B
ring finger protein 19B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary IBRDC3 is a cytolysis-associated transmembrane protein expressed in natural killer (NK) cells and T lymphocytes following cytokine stimulation (Kozlowski et al., 1999 [PubMed 10438909]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:32936445-32964685
Strand Reverse strand
Band p35.1
Transcripts
ENST00000373456 ENSP00000362555
ENST00000235150 ENSP00000235150
ENST00000356990 ENSP00000349482
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
Biological Process
GO:0016567 protein ubiquitination
GO:0042267 natural killer cell mediated cytotoxicity
GO:0072643 interferon-gamma secretion
Cellular Component
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
GO:0044194 cytolytic granule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Adaptive Immune System pathway
Immune System pathway
Antigen processing: Ubiquitination & Proteasome degradation pathway
Class I MHC mediated antigen processing & presentation pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.591504 Hs.602585
RefSeq NM_001127361 NM_001300826 NM_153341 XM_005270460 XM_006710356 XM_006710358
HUGO
OMIM
CCDS CCDS372 CCDS44107 CCDS72754
HPRD 13725
IMGT
EMBL
GenPept
RNA Seq Atlas