Version 5.4
Homo sapiens Gene: HIVEP3
Summary
InnateDB Gene IDBG-97154.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HIVEP3
Gene Name human immunodeficiency virus type I enhancer binding protein 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000127124
Encoded Proteins
IDBP-97156
human immunodeficiency virus type I enhancer binding protein 3
IDBP-97158
human immunodeficiency virus type I enhancer binding protein 3
IDBP-97160
human immunodeficiency virus type I enhancer binding protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the human immunodeficiency virus type 1 enhancer-binding protein family. Members of this protein family contain multiple zinc finger and acid-rich (ZAS) domains and serine-threonine rich regions. This protein acts as a transcription factor and is able to regulate nuclear factor kappaB-mediated transcription by binding the kappaB motif in target genes. This protein also binds the recombination signal sequence that flanks the V, D, and J regions of immunoglobulin and T-cell receptors. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:41506365-42035925
Strand Reverse strand
Band p34.2
Transcripts
ENST00000372584 ENSP00000361665
ENST00000372583 ENSP00000361664
ENST00000247584 ENSP00000247584
ENST00000460604
ENST00000489103
ENST00000491442
ENST00000479350
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 11 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0035914 skeletal muscle cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028634
View Gene Order
ENSBTAG00000020745
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.403972 Hs.596991 Hs.630532
RefSeq NM_001127714 NM_024503 XM_006710808 XM_006710809
HUGO
OMIM
CCDS CCDS44124 CCDS463
HPRD 09442
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca