Version 5.4
| Homo sapiens Gene: CYP4A22 | |||||||||||||||
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| Summary | |||||||||||||||
| InnateDB Gene | IDBG-98250.6 | ||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
| Gene Symbol | CYP4A22 | ||||||||||||||
| Gene Name | cytochrome P450, family 4, subfamily A, polypeptide 22 | ||||||||||||||
| Synonyms | CP4Y; CYP4A2; CYP4AII | ||||||||||||||
| Species | Homo sapiens | ||||||||||||||
| Ensembl Gene | ENSG00000162365 | ||||||||||||||
| Encoded Proteins |
cytochrome P450, family 4, subfamily A, polypeptide 22
cytochrome P450, family 4, subfamily A, polypeptide 22
cytochrome P450, family 4, subfamily A, polypeptide 22
cytochrome P450, family 4, subfamily A, polypeptide 22
cytochrome P450, family 4, subfamily A, polypeptide 22
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| Protein Structure | |||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
| Entrez Gene | |||||||||||||||
| Summary |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33. [provided by RefSeq, Jul 2008] This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||
| Type | Protein coding | ||||||||||||||
| Genomic Location | Chromosome 1:47137435-47149741 | ||||||||||||||
| Strand | Forward strand | ||||||||||||||
| Band | p33 | ||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||
| No orthologs found for this gene | |||||||||||||||
| Pathways | |||||||||||||||
| NETPATH | |||||||||||||||
| REACTOME |
Synthesis of Leukotrienes (LT) and Eoxins (EX) pathway
Arachidonic acid metabolism pathway
Fatty acids pathway
Miscellaneous substrates pathway
Eicosanoids pathway
Metabolism of lipids and lipoproteins pathway
Cytochrome P450 - arranged by substrate type pathway
Metabolism pathway
Biological oxidations pathway
Phase 1 - Functionalization of compounds pathway
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| KEGG |
Arachidonic acid metabolism pathway
Retinol metabolism pathway
Fatty acid degradation pathway
Vascular smooth muscle contraction pathway
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| INOH | |||||||||||||||
| PID NCI | |||||||||||||||
| Cross-References | |||||||||||||||
| SwissProt | |||||||||||||||
| TrEMBL | |||||||||||||||
| UniProt Splice Variant | |||||||||||||||
| Entrez Gene | |||||||||||||||
| UniGene | Hs.726474 | ||||||||||||||
| RefSeq | NM_001010969 XM_005270767 XM_005270768 | ||||||||||||||
| HUGO | |||||||||||||||
| OMIM | |||||||||||||||
| CCDS | CCDS30707 | ||||||||||||||
| HPRD | 16776 | ||||||||||||||
| IMGT | |||||||||||||||
| EMBL | |||||||||||||||
| GenPept | |||||||||||||||
| RNA Seq Atlas | |||||||||||||||