InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: CYP4A22

Summary

InnateDB Gene

IDBG-98250.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CYP4A22

Gene Name

cytochrome P450, family 4, subfamily A, polypeptide 22

Synonyms

CP4Y; CYP4A2; CYP4AII;

Species

Homo sapiens

Ensembl Gene

ENSG00000162365

Encoded Proteins

IDBP-98252

cytochrome P450, family 4, subfamily A, polypeptide 22

IDBP-98254

cytochrome P450, family 4, subfamily A, polypeptide 22

IDBP-98256

cytochrome P450, family 4, subfamily A, polypeptide 22

IDBP-808314

cytochrome P450, family 4, subfamily A, polypeptide 22

IDBP-808315

cytochrome P450, family 4, subfamily A, polypeptide 22

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33. [provided by RefSeq, Jul 2008]
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:47137435-47149741

Strand

Forward strand

Band

p33

Transcripts

ENST00000371891	ENSP00000360958
ENST00000371890	ENSP00000360957
ENST00000294337	ENSP00000294337
ENST00000490948
ENST00000485117
ENST00000620131	ENSP00000479019
ENST00000619754	ENSP00000482952

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004497	monooxygenase activity
GO:0005506	iron ion binding
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0018685	alkane 1-monooxygenase activity
GO:0020037	heme binding
GO:0052869	arachidonic acid omega-hydroxylase activity