Homo sapiens Gene: ST6GALNAC3
Summary
InnateDB Gene IDBG-99788.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ST6GALNAC3
Gene Name ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000184005
Encoded Proteins
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary ST6GALNAC3 belongs to a family of sialyltransferases that transfer sialic acids from CMP-sialic acid to terminal positions of carbohydrate groups in glycoproteins and glycolipids (Lee et al., 1999 [PubMed 10207017]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:76074719-76634601
Strand Forward strand
Band p31.1
Transcripts
ENST00000328299 ENSP00000329214
ENST00000464140
ENST00000621530 ENSP00000480283
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008373 sialyltransferase activity
Biological Process
GO:0006486 protein glycosylation
GO:0006677 glycosylceramide metabolic process
GO:0006687 glycosphingolipid metabolic process
GO:0009100 glycoprotein metabolic process
GO:0097503 sialylation
Cellular Component
GO:0000139 Golgi membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Pathways
NETPATH
REACTOME
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
O-linked glycosylation of mucins pathway
Asparagine N-linked glycosylation pathway
O-linked glycosylation pathway
Sialic acid metabolism pathway
Metabolism of proteins pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Termination of O-glycan biosynthesis pathway
KEGG
Glycosphingolipid biosynthesis pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q8NDV1
TrEMBL
UniProt Splice Variant
Entrez Gene 256435
UniGene Hs.337040 Hs.735443 Hs.738623
RefSeq NM_152996 XM_006710553
HUGO HGNC:19343
OMIM 610133
CCDS CCDS672
HPRD 15341
IMGT
EMBL AJ507291 AK091215 AY358540 BC059363 CH471059
GenPept AAH59363 AAQ88904 BAC03611 CAD45371 EAX06388
RNA Seq Atlas 256435