Version 5.4
Homo sapiens Gene: CTBS
Summary
InnateDB Gene IDBG-99985.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CTBS
Gene Name chitobiase, di-N-acetyl-
Synonyms CTB
Species Homo sapiens
Ensembl Gene ENSG00000117151
Encoded Proteins
IDBP-99987
chitobiase, di-N-acetyl-
IDBP-99989
chitobiase, di-N-acetyl-
IDBP-603790
chitobiase, di-N-acetyl-
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Chitobiase is a lysosomal glycosidase involved in degradation of asparagine-linked oligosaccharides on glycoproteins (Aronson and Kuranda, 1989 [PubMed 2531691]).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:84549606-84574480
Strand Reverse strand
Band p22.3
Transcripts
ENST00000370630 ENSP00000359664
ENST00000370625 ENSP00000359659
ENST00000477677
ENST00000465118 ENSP00000452177
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004568 chitinase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006032 chitin catabolic process
GO:0009313 oligosaccharide catabolic process
Cellular Component
GO:0005615 extracellular space
GO:0005764 lysosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028189
View Gene Order
ENSBTAG00000005782
Not yet available
Cross-References
SwissProt Q01459
TrEMBL F6X5H7
UniProt Splice Variant
Entrez Gene 1486
UniGene Hs.513557 Hs.668687 Hs.678773
RefSeq NM_004388
HUGO HGNC:2496
OMIM 600873
CCDS CCDS698
HPRD
IMGT
EMBL AF085700 AF085701 AF085702 AF085703 AF085704 AF085705 AF085706 AL359762 BC126333 BC126335 CH471097 M95767
GenPept AAA35684 AAC35852 AAI26334 AAI26336 CAH70207 EAW73232 EAW73233
RNA Seq Atlas 1486

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca