Homo sapiens Protein: ZNF326
Summary
InnateDB Protein IDBP-100209.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF326
Protein Name zinc finger protein 326
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000359476
InnateDB Gene IDBG-100201 (ZNF326)
Protein Structure
UniProt Annotation
Function Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. May play a role in neuronal differentiation and is able to bind DNA and activate expression in vitro. {ECO:0000269PubMed:22446626}.
Subcellular Localization Nucleus matrix {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 42 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 42 [view]
Protein-Protein 42 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR007071 A-kinase anchoring protein 95 (AKAP95)
PFAM PF04988
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q5BKZ1
TrEMBL
UniProt Splice Variant
Entrez Gene 284695
UniGene Hs.604906
RefSeq XP_005270836
HUGO HGNC:14104
OMIM 614601
CCDS
HPRD 15774
IMGT
EMBL
GenPept