Version 5.4
Homo sapiens Protein: SYPL2
Summary
InnateDB Protein IDBP-100824.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYPL2
Protein Name synaptophysin-like 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000358888
InnateDB Gene IDBG-100822 (SYPL2)
Protein Structure
UniProt Annotation
Function Involved in communication between the T-tubular and junctional sarcoplasmic reticulum (SR) membranes. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Triad junction, the junctional complex between the transverse tubule and the sarcoplasmic reticulum. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
Biological Process
GO:0006810 transport
GO:0006874 cellular calcium ion homeostasis
GO:0021762 substantia nigra development
Cellular Component
GO:0016020 membrane
GO:0030285 integral component of synaptic vesicle membrane
Protein Structure and Domains
PDB ID
InterPro IPR001285 Synaptophysin/synaptoporin
IPR008253 Marvel domain
PFAM PF01284
PRINTS PR00220
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5VXT5
PhosphoSite PhosphoSite-
TrEMBL B4DWF6
UniProt Splice Variant
Entrez Gene 284612
UniGene Hs.528366
RefSeq NP_001035799
HUGO HGNC:27638
OMIM
CCDS CCDS41365
HPRD 17478
IMGT
EMBL AB158472 AK131459 AK289513 AK293082 AK301509 AL355145 AL356735 CH471122
GenPept BAD18604 BAF82202 BAF85771 BAG63018 BAM08466 CAH70888 CAI22943 EAW56384

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca