InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: WARS2

Summary

InnateDB Protein

IDBP-101487.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

WARS2

Protein Name

tryptophanyl tRNA synthetase 2, mitochondrial

Synonyms

TrpRS;

Species

Homo sapiens

Ensembl Protein

ENSP00000358434

InnateDB Gene

IDBG-101485 (WARS2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Mitochondrion matrix.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004812	aminoacyl-tRNA ligase activity
GO:0004830	tryptophan-tRNA ligase activity
GO:0005524	ATP binding

Biological Process

GO:0006418	tRNA aminoacylation for protein translation
GO:0006436	tryptophanyl-tRNA aminoacylation
GO:0010467	gene expression

Cellular Component

GO:0005737	cytoplasm
GO:0005759	mitochondrial matrix

Protein Structure and Domains

PDB ID

InterPro

IPR002305 Aminoacyl-tRNA synthetase, class Ic
IPR002306 Tryptophan-tRNA ligase

PFAM

PF00579

PRINTS

PR01039

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9UGM6

PhosphoSite

PhosphoSite-Q9UGM6

TrEMBL

UniProt Splice Variant

Entrez Gene

10352

UniGene

Hs.523506

RefSeq

NP_957715

HUGO

HGNC:12730

OMIM

604733

CCDS

CCDS30817

HPRD

05295

IMGT

EMBL

AJ242739 AK223197 AK313740 AL139420 AL359823 AL590288 BC039889 BC044575 CH471122

GenPept

AAH44575 BAD96917 BAG36481 CAB63107 CAH71367 CAH71368 CAI21995 CAI21996 CAI22501 CAI22502 EAW56693