InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: WARS2

Summary

InnateDB Protein

IDBP-101489.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

WARS2

Protein Name

tryptophanyl tRNA synthetase 2, mitochondrial

Synonyms

TrpRS;

Species

Homo sapiens

Ensembl Protein

ENSP00000235521

InnateDB Gene

IDBG-101485 (WARS2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Mitochondrion matrix.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004812	aminoacyl-tRNA ligase activity
GO:0004830	tryptophan-tRNA ligase activity
GO:0005524	ATP binding

Biological Process

GO:0001570	vasculogenesis
GO:0006418	tRNA aminoacylation for protein translation
GO:0006436	tryptophanyl-tRNA aminoacylation
GO:0010467	gene expression

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix

Protein Structure and Domains

PDB ID

InterPro

IPR002305 Aminoacyl-tRNA synthetase, class Ic
IPR002306 Tryptophan-tRNA ligase

PFAM

PF00579

PRINTS

PR01039

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9UGM6

PhosphoSite

PhosphoSite-Q9UGM6

TrEMBL

B7Z5X7

UniProt Splice Variant

Entrez Gene

10352

UniGene

Hs.523506

RefSeq

NP_056651

HUGO

HGNC:12730

OMIM

604733

CCDS

CCDS900

HPRD

05295

IMGT

EMBL

AJ242739 AK223197 AK299547 AK313740 AL139420 AL359823 AL590288 BC039889 BC044575 CH471122

GenPept

AAH44575 BAD96917 BAG36481 BAH13063 CAB63107 CAH71367 CAH71368 CAI21995 CAI21996 CAI22501 CAI22502 EAW56693