Version 5.4
Homo sapiens Protein: APH1A
Summary
InnateDB Protein IDBP-102079.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APH1A
Protein Name anterior pharynx defective 1 homolog A (C. elegans)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000236017
InnateDB Gene IDBG-102071 (APH1A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 29 [view]
Protein-Protein 28 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0016485 protein processing
GO:0043085 positive regulation of catalytic activity
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR009294 Gamma-secretase subunit Aph-1
PFAM PF06105
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5TB21
UniProt Splice Variant
Entrez Gene 51107
UniGene Hs.735911
RefSeq
HUGO HGNC:29509
OMIM 607629
CCDS
HPRD
IMGT
EMBL AL138795
GenPept CAI22813

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca