InnateDB Protein
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IDBP-102386.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CGN
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Protein Name
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cingulin
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000271636
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InnateDB Gene
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IDBG-102382 (CGN)
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Protein Structure
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Function |
Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
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Subcellular Localization |
Cell junction, tight junction {ECO:0000250}. Note=Localizes to the apical junction complex composed of tight and adherens junctions. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Localized on the cytoplasmic face of tight junctions of polarized epithelia and some endothelia. Expressed in pancreas, kidney, liver and lung, but not in skeletal muscle, placenta, brain or heart.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
18
[view]
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Protein-Protein |
17
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
1
[view]
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002928
Myosin tail
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PFAM |
PF01576
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9P2M7
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PhosphoSite |
PhosphoSite-Q9P2M7
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TrEMBL |
A6PVU7
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UniProt Splice Variant |
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Entrez Gene |
57530
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UniGene |
Hs.705768
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RefSeq |
NP_065821
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HUGO |
HGNC:17429
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OMIM |
609473
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CCDS |
CCDS999
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HPRD |
10827
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IMGT |
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EMBL |
AB037740
AF263462
AK290007
AL365436
BC146657
BC152445
CH471121
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GenPept |
AAF74498
AAI46658
AAI52446
BAA92557
BAF82696
CAI16590
EAW53434
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