Homo sapiens Protein: HOXA4 | |||||||||||||
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Summary | |||||||||||||
InnateDB Protein | IDBP-10386.5 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | HOXA4 | ||||||||||||
Protein Name | homeobox A4 | ||||||||||||
Synonyms | HOX1; HOX1D; | ||||||||||||
Species | Homo sapiens | ||||||||||||
Ensembl Protein | ENSP00000353151 | ||||||||||||
InnateDB Gene | IDBG-10384 (HOXA4) | ||||||||||||
Protein Structure | |||||||||||||
UniProt Annotation | |||||||||||||
Function | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to sites in the 5'-flanking sequence of its coding region with various affinities. The consensus sequences of the high and low affinity binding sites are 5'-TAATGA[CG]-3' and 5'-CTAATTTT- 3'. | ||||||||||||
Subcellular Localization | Nucleus. | ||||||||||||
Disease Associations | |||||||||||||
Tissue Specificity | Embryonic nervous system. | ||||||||||||
Comments | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||
PDB ID | |||||||||||||
InterPro |
IPR001356
Homeobox domain IPR009057 Homeodomain-like IPR017995 Homeobox protein, antennapedia type IPR020479 Homeodomain, metazoa |
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PFAM |
PF00046
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PRINTS |
PR00025
PR00024 |
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PIRSF | |||||||||||||
SMART |
SM00389
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TIGRFAMs | |||||||||||||
Post-translational Modifications | |||||||||||||
Modification | |||||||||||||
Cross-References | |||||||||||||
SwissProt | Q00056 | ||||||||||||
PhosphoSite | PhosphoSite-Q00056 | ||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 3201 | ||||||||||||
UniGene | Hs.533357 | ||||||||||||
RefSeq | |||||||||||||
HUGO | HGNC:5105 | ||||||||||||
OMIM | 142953 | ||||||||||||
CCDS | CCDS5405 | ||||||||||||
HPRD | 00841 | ||||||||||||
IMGT | |||||||||||||
EMBL | AC004080 CH236948 CH471073 M28199 M74297 | ||||||||||||
GenPept | AAA53290 AAA58664 EAL24224 EAW93872 | ||||||||||||