InnateDB Protein
|
IDBP-104171.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
ARHGAP30
|
Protein Name
|
Rho GTPase activating protein 30
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000356992
|
InnateDB Gene
|
IDBG-104159 (ARHGAP30)
|
Protein Structure
|
|
Function |
GTPase-activating protein (GAP) for RAC1 and RHOA, but not for CDC42. {ECO:0000269PubMed:21565175}.
|
Subcellular Localization |
Cytoplasmic vesicle {ECO:0000269PubMed:21565175}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0005096
|
GTPase activator activity
|
|
Biological Process |
GO:0007165
|
signal transduction
|
GO:0007264
|
small GTPase mediated signal transduction
|
GO:0043547
|
positive regulation of GTPase activity
|
GO:0051056
|
regulation of small GTPase mediated signal transduction
|
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR000198
Rho GTPase-activating protein domain
IPR008936
Rho GTPase activation protein
|
PFAM |
PF00620
|
PRINTS |
|
PIRSF |
|
SMART |
SM00324
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q7Z6I6
|
PhosphoSite |
PhosphoSite-Q7Z6I6
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
257106
|
UniGene |
Hs.389374
|
RefSeq |
NP_001274529
|
HUGO |
HGNC:27414
|
OMIM |
614264
|
CCDS |
CCDS30918
|
HPRD |
11250
|
IMGT |
|
EMBL |
AK160366
AL591806
BC043387
BC053688
BX537846
|
GenPept |
AAH43387
AAH53688
BAD18709
CAD97855
CAI15373
CAI15374
CAI15375
|
|
|