Version 5.4
Homo sapiens Protein: BRP44
Summary
InnateDB Protein IDBP-104582.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BRP44
Protein Name brain protein 44
Synonyms BRP44;
Species Homo sapiens
Ensembl Protein ENSP00000271373
InnateDB Gene IDBG-104578 (BRP44)
Protein Structure
UniProt Annotation
Function Mediates the uptake of pyruvate into mitochondria. {ECO:0000269PubMed:22628558}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000269PubMed:22628558}; Multi-pass membrane protein {ECO:0000269PubMed:22628558}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006090 pyruvate metabolic process
GO:0006850 mitochondrial pyruvate transport
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR005336 Mitochondrial pyruvate carrier
PFAM PF03650
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95563
PhosphoSite PhosphoSite-O95563
TrEMBL Q5R3B4
UniProt Splice Variant
Entrez Gene 25874
UniGene Hs.636120
RefSeq NP_001137146
HUGO HGNC:24515
OMIM 614737
CCDS CCDS1266
HPRD 08525
IMGT
EMBL AK290126 AL035304 AL110297 BC104157 BC104158 CH471067 CR407632 CR533473 Z97876
GenPept AAI04158 AAI04159 BAF82815 CAA22909 CAB53738 CAG28560 CAG38504 CAI20075 EAW90814 EAW90815 EAW90816

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca