Version 5.4
Homo sapiens Protein: GORAB
Summary
InnateDB Protein IDBP-104753.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GORAB
Protein Name golgin, RAB6-interacting
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000356736
InnateDB Gene IDBG-104749 (GORAB)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm. Golgi apparatus.
Disease Associations Geroderma osteodysplasticum (GO) [MIM:231070]: A rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation. {ECO:0000269PubMed:18997784}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5T7V8
PhosphoSite PhosphoSite-Q5T7V8
TrEMBL
UniProt Splice Variant
Entrez Gene 92344
UniGene Hs.736933
RefSeq NP_001139511
HUGO HGNC:25676
OMIM 607983
CCDS CCDS53428
HPRD 12144
IMGT
EMBL AF143889 AK021814 AL162399 BC047476 BC064945
GenPept AAD32702 AAH47476 AAH64945 BAB13903 CAI15420 CAI15421

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca