InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ANGPTL1

Summary

InnateDB Protein

IDBP-105084.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ANGPTL1

Protein Name

angiopoietin-like 1

Synonyms

ANG3; ANGPT3; AngY; ARP1; dJ595C2.2; UNQ162;

Species

Homo sapiens

Ensembl Protein

ENSP00000234816

InnateDB Gene

IDBG-105082 (ANGPTL1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Secreted {ECO:0000269PubMed:10025962}.

Disease Associations

Tissue Specificity

Highly expressed in adrenal gland, placenta, thyroid gland, heart, skeletal muscle and small intestine. Weakly expressed in testis, ovary, colon, pancreas, kidney and stomach. {ECO:0000269PubMed:10025962}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding

Biological Process

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0005615	extracellular space
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain

PFAM

PF00147

PRINTS

PIRSF

SMART

SM00186

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O95841

PhosphoSite

PhosphoSite-O95841

TrEMBL

A0A024R908

UniProt Splice Variant

Entrez Gene

9068

UniGene

Hs.660962

RefSeq

NP_004664

HUGO

HGNC:489

OMIM

603874

CCDS

CCDS1327

HPRD

04851

IMGT

EMBL

AB056476 AF107253 AL355520 AY358278 BC050640 CH471067

GenPept

AAD19608 AAH50640 AAQ88645 BAB40691 CAC13169 CAI21921 EAW91032 EAW91033