Version 5.4
Homo sapiens Protein: TOR3A
Summary
InnateDB Protein IDBP-105098.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TOR3A
Protein Name torsin family 3, member A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000335351
InnateDB Gene IDBG-105090 (TOR3A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm. Endoplasmic reticulum lumen.
Disease Associations
Tissue Specificity Ubiquitously expressed. Highest expression in stomach, salivary glands and lymph nodes. Isoform 2 is expressed in placenta. {ECO:0000269PubMed:11863361}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0016887 ATPase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0051085 chaperone mediated protein folding requiring cofactor
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR010448 Torsin
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF06309
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H497
PhosphoSite PhosphoSite-Q9H497
TrEMBL
UniProt Splice Variant
Entrez Gene 64222
UniGene Hs.584957
RefSeq
HUGO HGNC:11997
OMIM 607555
CCDS
HPRD 09615
IMGT
EMBL AJ299403 AJ299441 AJ318044 AJ318045 AJ318046 AJ318047 AJ318048 AJ318049 AJ318050 AK025998 AK299966 AK316530 AL139132 BC001085 BC007571 BC011746 BC018292 BC088368 CR457354
GenPept AAH01085 AAH07571 AAH11746 AAH18292 AAH88368 BAB15312 BAG61792 BAH14901 CAC13973 CAC14461 CAC88129 CAC88130 CAG33635 CAH70928 CAH70929

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca