Homo sapiens Protein: TNNT2
Summary
InnateDB Protein IDBP-105745.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TNNT2
Protein Name troponin T type 2 (cardiac)
Synonyms CMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TnTC;
Species Homo sapiens
Ensembl Protein ENSP00000236918
InnateDB Gene IDBG-105731 (TNNT2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005200 structural constituent of cytoskeleton
GO:0005523 tropomyosin binding
GO:0016887 ATPase activity
GO:0030172 troponin C binding
GO:0031013 troponin I binding
Biological Process
GO:0006200 ATP catabolic process
GO:0006936 muscle contraction
GO:0006937 regulation of muscle contraction
GO:0007507 heart development
GO:0008016 regulation of heart contraction
GO:0030049 muscle filament sliding
GO:0032780 negative regulation of ATPase activity
GO:0032781 positive regulation of ATPase activity
GO:0045214 sarcomere organization
GO:0051592 response to calcium ion
GO:0055009 atrial cardiac muscle tissue morphogenesis
GO:0055010 ventricular cardiac muscle tissue morphogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005861 troponin complex
GO:0005865 striated muscle thin filament
GO:0030016 myofibril
GO:0030017 sarcomere
Protein Structure and Domains
PDB ID
InterPro IPR001978 Troponin
PFAM PF00992
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8IZA1
UniProt Splice Variant
Entrez Gene 7139
UniGene Hs.533613
RefSeq NP_001263274
HUGO HGNC:11949
OMIM 191045
CCDS CCDS73003
HPRD 01844
IMGT
EMBL AC119427 AF004409 AF004410 AF004411 AF004412 AF004413 AF004414 AF004415 AF004416 AF004417 AF004418 AF004419 AF004420 AF004421 AF004422 AK290621 AY044273 AY160216 BC002653 EF179183 EU099967 EU099968 EU099969 L40162 S64668 S71126 S71127 S71128 X74819 X79855 X79856 X79857 X79858 Y09626 Y09627 Y09628
GenPept AAA67422 AAB27731 AAB30956 AAB30957 AAC39590 AAH02653 AAK92231 AAN71651 ABN05286 ABV48784 ABV48785 ABV48786 BAF83310 CAA52818 CAA56235 CAA56236 CAA56237 CAA56238 CAA70839 CAA70840 CAA70841