InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LAX1

Summary

InnateDB Protein

IDBP-105974.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LAX1

Protein Name

lymphocyte transmembrane adaptor 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000356186

InnateDB Gene

IDBG-105972 (LAX1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0042169	SH2 domain binding

Biological Process

GO:0000188	inactivation of MAPK activity
GO:0006955	immune response
GO:0035556	intracellular signal transduction
GO:0042113	B cell activation
GO:0050868	negative regulation of T cell activation

Cellular Component

GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8IWV1

PhosphoSite

PhosphoSite-Q8IWV1

TrEMBL

UniProt Splice Variant

Entrez Gene

54900

UniGene

Hs.272794

RefSeq

NP_001269807

HUGO

HGNC:26005

OMIM

CCDS

CCDS44297

HPRD

08312

IMGT

EMBL

AC114402 AK000347 AK301421 AY090784 BC069650 BC089408 CH471067

GenPept

AAH69650 AAH89408 AAM09818 BAA91101 BAH13480 EAW91491