InnateDB Protein
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IDBP-107621.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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LGALS8
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Protein Name
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lectin, galactoside-binding, soluble, 8
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Synonyms
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Gal-8; PCTA-1; PCTA1; Po66-CBP;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000355543
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InnateDB Gene
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IDBG-107605 (LGALS8)
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Protein Structure
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Function |
Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans. {ECO:0000269PubMed:21288902}.
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Subcellular Localization |
Cytoplasm {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Ubiquitous. Selective expression by prostate carcinomas versus normal prostate and benign prostatic hypertrophy.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
36
[view]
|
Protein-Protein |
34
[view]
|
Protein-DNA |
2
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001079
Galectin, carbohydrate recognition domain
IPR008985
Concanavalin A-like lectin/glucanases superfamily
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PFAM |
PF00337
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PRINTS |
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PIRSF |
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SMART |
SM00276
SM00908
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TIGRFAMs |
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Modification |
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SwissProt |
O00214
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PhosphoSite |
PhosphoSite-O00214
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TrEMBL |
E9PPL1
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UniProt Splice Variant |
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Entrez Gene |
3964
|
UniGene |
Hs.735982
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RefSeq |
NP_963838
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HUGO |
HGNC:6569
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OMIM |
606099
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CCDS |
CCDS1612
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HPRD |
09356
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IMGT |
|
EMBL |
AF074000
AF074001
AF074002
AF193805
AF193806
AF342815
AF342816
AF468213
AL136105
AL359921
BC015818
BC016486
L78132
X91790
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GenPept |
AAB51605
AAD45402
AAD45403
AAD45404
AAF19370
AAH15818
AAH16486
AAK16735
AAK16736
AAL77076
CAA62904
CAI13773
CAI13774
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