InnateDB Protein
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IDBP-10938.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PARVG
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Protein Name
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parvin, gamma
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000349378
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InnateDB Gene
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IDBG-10936 (PARVG)
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Protein Structure
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Function |
Probably plays a role in the regulation of cell adhesion and cytoskeleton organization. {ECO:0000250}.
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Subcellular Localization |
Cell junction, focal adhesion. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Constituent of focal adhesions. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed predominantly in lymphoid organs, including spleen, thymus, lymph node, bone marrow and peripheral blood leukocytes and moderately in the digestive tract, including stomach, duodenum, jejunum, ileum, ileocecum and appendix, as well as in lung and liver. Also expressed in tumors, but at a lower level than in the corresponding normal tissues. {ECO:0000269PubMed:11722847}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
7
[view]
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Protein-Protein |
7
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001715
Calponin homology domain
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PFAM |
PF00307
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PRINTS |
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PIRSF |
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SMART |
SM00033
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TIGRFAMs |
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Modification |
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SwissProt |
Q9HBI0
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PhosphoSite |
PhosphoSite-Q9HBI0
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TrEMBL |
B0QYM9
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UniProt Splice Variant |
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Entrez Gene |
64098
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UniGene |
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RefSeq |
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HUGO |
HGNC:14654
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OMIM |
608122
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CCDS |
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HPRD |
16285
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IMGT |
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EMBL |
AF237772
AK293360
AK307294
AL031595
AL355092
AL590887
BC034406
CR456480
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GenPept |
AAG27174
AAH34406
BAG56876
CAB90188
CAC37414
CAG30366
CAI22314
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