Version 5.4
Homo sapiens Protein: ALDH6A1
Summary
InnateDB Protein IDBP-11884.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALDH6A1
Protein Name aldehyde dehydrogenase 6 family, member A1
Synonyms MMSADHA; MMSDH;
Species Homo sapiens
Ensembl Protein ENSP00000342564
InnateDB Gene IDBG-11882 (ALDH6A1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000062 fatty-acyl-CoA binding
GO:0004491 methylmalonate-semialdehyde dehydrogenase (acylating) activity
GO:0016491 oxidoreductase activity
GO:0018478 malonate-semialdehyde dehydrogenase (acetylating) activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006210 thymine catabolic process
GO:0006573 valine metabolic process
GO:0006574 valine catabolic process
GO:0008152 metabolic process
GO:0009083 branched-chain amino acid catabolic process
GO:0019859 thymine metabolic process
GO:0034641 cellular nitrogen compound metabolic process
GO:0044281 small molecule metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR010061 Methylmalonate-semialdehyde dehydrogenase
IPR015590 Aldehyde dehydrogenase domain
IPR016161 Aldehyde/histidinol dehydrogenase
PFAM PF00171
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q02252
PhosphoSite PhosphoSite-Q02252
TrEMBL G3V4Z4
UniProt Splice Variant
Entrez Gene 4329
UniGene Hs.732227
RefSeq NP_001265522
HUGO HGNC:7179
OMIM 603178
CCDS CCDS61501
HPRD 04416
IMGT
EMBL AC005484 AF148505 AF148855 AF159889 AJ249994 AK294243 AK312389 BC004909 BC032371 CH471061 M93405
GenPept AAA36328 AAF04489 AAF80380 AAG29581 AAH04909 AAH32371 BAG35306 BAG57539 CAB76468 EAW81159

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca